Business Type:Manufacturer
Country/Region:China
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HOT Rank
8/10
Jinan Jianfeng Chemical CO., ltd
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Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
8/10
Tianeptin sodium
Tianeptine, sold under the brand names Stablon and Coaxil among others, is an atypical antidepressant powder.
Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects.
Formal Name
7-[(3-chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]-heptanoic acid, monosodium salt
CAS Number
30123-17-2
Molecular Formula
C21H24ClN2O4S • Na
Formula Weight
458.9
Tianeptine is a tricyclic antidepressant that enhances serotonin uptake. This drug can affect neuroprotection, neuronal excitability, memory and anxiety. However, tianeptine is not linked to adverse psychomotor, cognitive, cardiovascular, sleep and bodyweight effects. The drug has a low tendency for abuse and has a positive pharmacokinetic profile.
Tianeptine is least involved in drug interaction as it is not metabolized by cytochrome P450 system in the liver. In hippocampus and amygdala, tianeptine is involved in glutamatergic transmission processes and elicits neuroplasticity.